StarBase has been updated to explore Pan-Cancer pattern of lncRNAs, miRNAs, RNA-binding proteins (RBP) and their regulatory networks (ceRNA, coexpression) by mining expression profiles of miRNAs, lncRNAs and mRNAs across 14 cancer types (>6000 samples) from The Cancer Genome Atlas (TCGA) Data Portal (all data available without limitations).StarBase provides the following Pan-Cancer Analysis Services:
- starBase constructed Pan-Cancer expression profiles of lncRNAs, miRNAs from TCGA RNA-Seq and miRNA-Seq data.
- starBase generated Pan-Cancer networks of CLIP-Seq experimentally supported miRNA-lncRNA and miRNA-mRNA interactions.
- starBase identified Pan-Cancer ceRNA networks involving lncRNAs and mRNAs by analyzing >6000 tumor and normal samples and CLIP-Seq suppored miRNA-target interactions.
- starBase firstly provided Pan-Cancer maps of interactions between RNA-binding proteins (RBPs) and RNAs(lncRNAs, mRNAs).
- starBase provides interactive BarPlot, ScatterPlot and BoxPlot charts to show the above-mentioned genes and regulatory networks.
starBase Pan-Cancer Analysis is freely available at http://starbase.sysu.edu.cn/
Related posts:
- starBase v2.0: decoding miRNA-ncRNA, miRNA-ceRNA and protein-RNA interaction maps from large-scale CLIP-Seq data
- starBase: a database for exploring microRNA–mRNA interaction maps
- ChIPBase: decoding the transcriptional regulation of microRNA and lncRNA genes from ChIP-Seq data
